ITM6026
ITM6026
- Catalog: ITM6026
- Gene/Protein: CEACAM5 CEA
- Product Description: Immunotag™ carcinoembryonic antigen(CEA) (ABT-CEA) mouse mAb
490.0000
Price in reward points: 490
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CEA (4A1) |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p |
| Recommended Dilution | IHC-p 1:100-500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Synthesized peptide derived from human carcinoembryonic antigen(CEA) |
| Specificity | This antibody detects endogenous levels of human carcinoembryonic antigen(CEA) |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CEACAM5 CEA |
| Accession No. | P06731 |
| Alternate Names | Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e) |
| Description | carcinoembryonic antigen related cell adhesion molecule 5(CEACAM5) Homo sapiens This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015], |
| Protein Expression | Colon,Colon carcinoma,Liver,Saliva, |
| Subcellular Localization | Cytoplasmic |
| Protein Function | function:Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.,PTM:Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 7 Ig-like (immunoglobulin-like) domains.,subunit:Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.,tissue specificity:Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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