ITN0002
ITN0002
- Catalog: ITN0002
- Gene/Protein: LCP1 PLS2
- Product Description: Immunotag™ PLSL Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PLSL |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1-80 |
| Specificity | PLSL Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | LCP1 PLS2 |
| Accession No. | P13796 Q61233 |
| Description | lymphocyte cytosolic protein 1(LCP1) Homo sapiens Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008], |
| Protein Expression | Amygdala,Brain,Lymph,Placenta,T-cell,Thymus, |
| Subcellular Localization | stress fiber,ruffle,phagocytic cup,podosome,extracellular space,cytoplasm,cytosol,actin filament,plasma membrane,focal adhesion,actin cytoskeleton,filopodium,actin filament bundle,ruffle membrane,GO |
| Protein Function | function:Actin-binding protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia.,PTM:Phosphorylated.,PTM:The N-terminus is blocked.,similarity:Contains 2 actin-binding domains.,similarity:Contains 2 EF-hand domains.,similarity:Contains 4 CH (calponin-homology) domains.,subunit:Monomer.,tissue specificity:Restricted to the spleen and other lymph node-containing organs. Expressed in neutrophils, monocytes, B lymphocytes, and myeloid cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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