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ITN0002

ITN0002
  • Gene/Protein: LCP1 PLS2
  • Product Description: Immunotag™ PLSL Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ PLSL Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PLSL
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein . at AA range: 1-80
Specificity PLSL Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name LCP1 PLS2
Accession No. P13796 Q61233
Description lymphocyte cytosolic protein 1(LCP1) Homo sapiens Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008],
Protein Expression Amygdala,Brain,Lymph,Placenta,T-cell,Thymus,
Subcellular Localization stress fiber,ruffle,phagocytic cup,podosome,extracellular space,cytoplasm,cytosol,actin filament,plasma membrane,focal adhesion,actin cytoskeleton,filopodium,actin filament bundle,ruffle membrane,GO
Protein Function function:Actin-binding protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia.,PTM:Phosphorylated.,PTM:The N-terminus is blocked.,similarity:Contains 2 actin-binding domains.,similarity:Contains 2 EF-hand domains.,similarity:Contains 4 CH (calponin-homology) domains.,subunit:Monomer.,tissue specificity:Restricted to the spleen and other lymph node-containing organs. Expressed in neutrophils, monocytes, B lymphocytes, and myeloid cells.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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