ITN0067
ITN0067
- Catalog: ITN0067
- Gene/Protein: SYN2
- Product Description: Immunotag™ SYN2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SYN2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 370-450 |
| Specificity | SYN2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SYN2 |
| Accession No. | Q92777 Q64332 Q63537 |
| Description | synapsin II(SYN2) Homo sapiens This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction. |
| Protein Expression | Brain, |
| Subcellular Localization | plasma membrane,synaptic vesicle,cell junction,synaptic vesicle membrane,SNARE complex,myelin sheath,synapse, |
| Protein Function | caution:There are several mRNAs and ESTs supporting this gene model. However the genome sequence encoding the N-terminal part contains several sequence discrepencies.,function:Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release.,sequence caution:Several in-frame stop codons.,similarity:Belongs to the synapsin family.,subunit:Interacts with CAPON.,tissue specificity:Central and peripheral nervous systems., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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