ITN0077
ITN0077
- Catalog: ITN0077
- Gene/Protein: NKRF ITBA4 NRF
- Product Description: Immunotag™ NKRF Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NKRF |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 550-630 |
| Specificity | NKRF Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | NKRF ITBA4 NRF |
| Accession No. | O15226 Q8BY02 |
| Description | NFKB repressing factor(NKRF) Homo sapiens This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010], |
| Protein Expression | Brain,Cervix carcinoma,Pancreas,Skin, |
| Subcellular Localization | nucleus,nucleoplasm,nucleolus,endoplasmic reticulum, |
| Protein Function | function:Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.,similarity:Contains 1 G-patch domain.,similarity:Contains 1 R3H domain.,subunit:Interacts with NF-kappa-B.,tissue specificity:Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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