ITN0078
ITN0078
- Catalog: ITN0078
- Gene/Protein: FOXN1 RONU WHN
- Product Description: Immunotag™ FOXN1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | FOXN1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 340-420 |
Specificity | FOXN1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | FOXN1 RONU WHN |
Accession No. | O15353 Q61575 |
Description | forkhead box N1(FOXN1) Homo sapiens Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008], |
Protein Expression | Thymus, |
Subcellular Localization | nucleus, |
Protein Function | disease:Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy [MIM:601705].,function:Transcriptional regulator involved in development.,online information:FOXN1 mutation db,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Expressed in thymus., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |