ITN0098
ITN0098
- Catalog: ITN0098
- Gene/Protein: SNRPD3
- Product Description: Immunotag™ SMD3 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | SMD3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
Specificity | SMD3 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | SNRPD3 |
Accession No. | P62318 P62320 |
Description | small nuclear ribonucleoprotein D3 polypeptide(SNRPD3) Homo sapiens This gene encodes a core component of the spliceosome, which is a nuclear ribonucleoprotein complex that functions in pre-mRNA splicing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
Cell Pathway/ Category | Spliceosome,Systemic lupus erythematosus, |
Protein Expression | Lung, |
Subcellular Localization | commitment complex,nucleoplasm,spliceosomal complex,U5 snRNP,U7 snRNP,U1 snRNP,U2 snRNP,U4 snRNP,U12-type spliceosomal complex,telomerase holoenzyme complex,cytoplasm,cytosol,small nuclear ribo |
Protein Function | disease:In the autoimmune disease systemic lupus erythematosus, antinuclear antibodies are developed with Sm specificity.,PTM:Arg-97 is dimethylated, probably to asymmetric dimethylarginine.,PTM:Methylated on arginine residues by PRMT5 and PRMT7; methylation is required for assembly and biogenesis of snRNPs.,similarity:Belongs to the snRNP core protein family.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |