ITN0104
ITN0104
- Catalog: ITN0104
- Gene/Protein: FOXM1 FKHL16 HFH11 MPP2 WIN
- Product Description: Immunotag™ FOXM1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FOXM1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 190-270 |
| Specificity | FOXM1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | FOXM1 FKHL16 HFH11 MPP2 WIN |
| Accession No. | Q08050 O08696 P97691 |
| Description | forkhead box M1(FOXM1) Homo sapiens The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011], |
| Protein Expression | Colon carcinoma,Epithelium,Lung,Lymphoblast,Ovary,Pancreatic carcinoma,Skin,Testis, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm, |
| Protein Function | Isoform 1 and isoform 2 appear to be the only activators of gene transcription. Isoform 3, found in rat, does not seem to exist in human,developmental stage:Embryonic expression pattern: liver, lung, intestine, kidney, urinary tract; adult expression pattern: intestine, colon, testis and thymus.,domain:Within the protein there is a domain which acts as a transcriptional activator. Insertion of a splicing sequence within it inactivates this transcriptional activity, as it is the case for isoform 4.,function:Transcriptional activatory factor. May play a role in the control of cell proliferation.,induction:Induced during liver regeneration and oxidative stress.,PTM:Phosphorylated in M (mitotic) phase.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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