ITN0202
ITN0202
- Catalog: ITN0202
- Gene/Protein: FRAT1
- Product Description: Immunotag™ FRAT1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FRAT1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 130-210 |
| Specificity | FRAT1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | FRAT1 |
| Accession No. | Q92837 P70339 |
| Description | frequently rearranged in advanced T-cell lymphomas 1(FRAT1) Homo sapiens The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008], |
| Cell Pathway/ Category | WNT,WNT-T CELL |
| Protein Expression | Lung,Testis, |
| Subcellular Localization | cytosol, |
| Protein Function | function:Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.,PTM:Phosphorylated.,similarity:Belongs to the GSK-3-binding protein family.,subunit:Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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