ITN0204
ITN0204
- Catalog: ITN0204
- Gene/Protein: GTSE1
- Product Description: Immunotag™ GTSE1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | GTSE1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 70-150 |
Specificity | GTSE1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | GTSE1 |
Accession No. | Q9NYZ3 Q8R080 |
Description | G2 and S-phase expressed 1(GTSE1) Homo sapiens The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | p53, |
Protein Expression | Brain,Epithelium,Liver,Muscle,Placenta, |
Subcellular Localization | nucleoplasm,cytosol,cytoplasmic microtubule,membrane, |
Protein Function | developmental stage:Expressed in G2/M phase. Not detected in quiescent cells.,function:May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.,PTM:Phosphorylated in mitosis.,subcellular location:Associated with microtubules., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |