ITN0262
ITN0262
- Catalog: ITN0262
- Gene/Protein: LAMTOR2 MAPBPIP ROBLD3 HSPC003
- Product Description: Immunotag™ LTOR2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LTOR2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Specificity | LTOR2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | LAMTOR2 MAPBPIP ROBLD3 HSPC003 |
| Accession No. | Q9Y2Q5 Q9JHS3 |
| Description | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2(LAMTOR2) Homo sapiens The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009], |
| Protein Expression | Lung,Umbilical cord blood, |
| Subcellular Localization | lysosomal membrane,late endosome,endosome membrane,extracellular exosome,Ragulator complex, |
| Protein Function | disease:Defects in ROBLD3 are the cause of immunodeficiency due to defect in MAPBP-interacting protein [MIM:610798]. This form of primary immunodeficiency syndrome includes congenital neutropenia, partial albinism, short stature and B-cell and cytotoxic T-cell deficiency.,function:Adapter protein that enhances the efficiency of the MAP kinase cascade. Facilitates the activation of MAPK2.,online information:ROBLD3 mutation db,similarity:Belongs to the GAMAD family.,subunit:Heterodimer with MAP2K1IP1. Interacts with MAPK1 and MAP2K1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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