ITN0264
ITN0264
- Catalog: ITN0264
- Gene/Protein: MX1
- Product Description: Immunotag™ MX1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | MX1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 500-580 |
Specificity | MX1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | MX1 |
Accession No. | P20591 P09922 P18588 |
Description | MX dynamin like GTPase 1(MX1) Homo sapiens This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], |
Protein Expression | Primary B-Cells,Spleen,Uterus, |
Subcellular Localization | nucleus,cytoplasm,endoplasmic reticulum membrane,cytosol,nuclear membrane,perinuclear region of cytoplasm, |
Protein Function | function:May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus.,induction:By interferons.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,subunit:Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |