ITN0329
ITN0329
- Catalog: ITN0329
- Gene/Protein: SATB2 KIAA1034
- Product Description: Immunotag™ SATB2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SATB2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 650-730 |
| Specificity | SATB2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SATB2 KIAA1034 |
| Accession No. | Q9UPW6 Q8VI24 |
| Description | SATB homeobox 2(SATB2) Homo sapiens This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Feb 2010], |
| Protein Expression | Brain,Colon,PCR rescued clones, |
| Subcellular Localization | histone deacetylase complex,nucleus,nucleoplasm,transcription factor complex,cytoplasm,nuclear matrix, |
| Protein Function | disease:Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11).,disease:Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation.,function:May play an important role in palate formation.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 CUT DNA-binding domains.,tissue specificity:High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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