ITN0464
ITN0464
- Catalog: ITN0464
- Gene/Protein: RBFOX1 A2BP A2BP1 FOX1 HRNBP1
- Product Description: Immunotag™ RFOX1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RFOX1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 50-130 |
| Specificity | RFOX1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RBFOX1 A2BP A2BP1 FOX1 HRNBP1 |
| Accession No. | Q9NWB1 Q9JJ43 |
| Description | RNA binding protein, fox-1 homolog 1(RBFOX1) Homo sapiens The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011], |
| Protein Expression | Brain, |
| Subcellular Localization | nucleus,cytoplasm,trans-Golgi network, |
| Protein Function | function:RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to the C-terminal of ATXN2.,tissue specificity:Predominantly expressed in muscle and brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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