ITN0544
ITN0544
- Catalog: ITN0544
- Gene/Protein: CTAG2 ESO2 LAGE1
- Product Description: Immunotag™ CTAG2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CTAG2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | CTAG2 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | CTAG2 ESO2 LAGE1 |
Accession No. | O75638 |
Description | cancer/testis antigen 2(CTAG2) Homo sapiens This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], |
Protein Expression | Hepatoma,Melanoma,Placenta,Stomach cancer, |
Subcellular Localization | centrosome, |
Protein Function | domain:A transmembrane domain is present in isoform LAGE-1A.,similarity:Belongs to the CTAG family.,tissue specificity:Testis and very low level in placenta and in some uterus samples. Observed in 25-50% of tumor samples of melanomas, non-small-cell lung carcinomas, bladder, prostate and head and neck cancers., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |