ITN0590
ITN0590
- Catalog: ITN0590
- Gene/Protein: SLC18A1 VAT1 VMAT1
- Product Description: Immunotag™ VMAT1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | VMAT1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | VMAT1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | SLC18A1 VAT1 VMAT1 |
Accession No. | P54219 Q8R090 Q01818 |
Description | solute carrier family 18 member A1(SLC18A1) Homo sapiens The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008], |
Cell Pathway/ Category | Parkinson's disease, |
Protein Expression | Brain,Pheochromocytoma, |
Subcellular Localization | endoplasmic reticulum membrane,integral component of plasma membrane,integral component of membrane,synaptic vesicle membrane,terminal bouton,clathrin-sculpted monoamine transport vesicle membrane, |
Protein Function | function:Involved in the vesicular transport of biogenic amines.,similarity:Belongs to the major facilitator superfamily. Vesicular transporter family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |