ITN0608
ITN0608
- Catalog: ITN0608
- Gene/Protein: DENND4A IRLB MYCPBP
- Product Description: Immunotag™ MYCPP Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | MYCPP |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | MYCPP Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | DENND4A IRLB MYCPBP |
Accession No. | Q7Z401 |
Description | DENN domain containing 4A(DENND4A) Homo sapiens This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016], |
Protein Expression | Brain,Cervix,Spinal cord,Uterus, |
Subcellular Localization | nucleus, |
Protein Function | developmental stage:Highly expressed in fetal liver.,function:Binds to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.,induction:Induced by serum in low-passage fibroblasts.,similarity:Contains 1 dDENN domain.,similarity:Contains 1 DENN domain.,similarity:Contains 1 uDENN domain.,similarity:Contains 2 PPR (pentatricopeptide) repeats.,tissue specificity:Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells. Expression is regulated in a growth- and cell cycle-dependent manner., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |