ITN0629
ITN0629
- Catalog: ITN0629
- Gene/Protein: DYNC1I2 DNCI2 DNCIC2
- Product Description: Immunotag™ DC1I2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DC1I2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | DC1I2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | DYNC1I2 DNCI2 DNCIC2 |
| Accession No. | Q13409 O88487 Q62871 |
| Description | dynein cytoplasmic 1 intermediate chain 2(DYNC1I2) Homo sapiens This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012], |
| Protein Expression | Brain,Cajal-Retzius cell,Endometrium,Epithelium,Kidney,Skin |
| Subcellular Localization | cytoplasm,centrosome,cytosol,cytoplasmic dynein complex,microtubule,vesicle, |
| Protein Function | function:The intermediate chains seem to help dynein bind to dynactin 150 kDa component.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Unlikely isoform. Several sequence problems.,similarity:Belongs to the dynein intermediate chain family.,similarity:Contains 7 WD repeats.,subunit:Consists of at least two heavy chains and a number of intermediate and light chains., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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