ITN0649
ITN0649
- Catalog: ITN0649
- Gene/Protein: GINS2 PSF2 CGI-122 DC5 HSPC037
- Product Description: Immunotag™ PSF2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PSF2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | PSF2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | GINS2 PSF2 CGI-122 DC5 HSPC037 |
| Accession No. | Q9Y248 Q9D600 |
| Description | GINS complex subunit 2(GINS2) Homo sapiens The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008], |
| Protein Expression | Brain,Dendritic cell,Umbilical cord blood, |
| Subcellular Localization | GINS complex,nucleus,nucleoplasm,replication fork protection complex, |
| Protein Function | function:The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.,mass spectrometry:This is the measured mass for the GINS complex PubMed:17557111,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the GINS2/PSF2 family.,subunit:Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS3. GINS complex interacts with DNA primase in vitro., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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