ITN0661
ITN0661
- Catalog: ITN0661
- Gene/Protein: POLR2I
- Product Description: Immunotag™ RPB9 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RPB9 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | RPB9 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | POLR2I |
| Accession No. | P36954 P60898 |
| Description | RNA polymerase II subunit I(POLR2I) Homo sapiens This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism,RNA polymerase,Huntington's disease, |
| Protein Expression | Brain,Uterus, |
| Subcellular Localization | nucleus,nucleoplasm,DNA-directed RNA polymerase II, core complex,nucleolus, |
| Protein Function | function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.,similarity:Contains 1 TFIIS-type zinc finger.,subunit:Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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