ITN0671
ITN0671
- Catalog: ITN0671
- Gene/Protein: DYNLRB1 BITH DNCL2A DNLC2A ROBLD1 HSPC162
- Product Description: Immunotag™ DLRB1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DLRB1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | DLRB1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | DYNLRB1 BITH DNCL2A DNLC2A ROBLD1 HSPC162 |
| Accession No. | Q9NP97 P62627 P62628 |
| Description | dynein light chain roadblock-type 1(DYNLRB1) Homo sapiens This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013], |
| Protein Expression | Fetal brain cortex,Hematopoietic stem cell,Kidney,Liver,Lymph,Place |
| Subcellular Localization | cytoplasm,centrosome,cytoplasmic dynein complex,microtubule,membrane,dynein complex,primary cilium,ciliary tip, |
| Protein Function | Additional isoforms seem to exist,function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport.,miscellaneous:Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients.,similarity:Belongs to the GAMAD family.,subunit:Homodimer.,tissue specificity:High expression in heart, liver, brain and pancreas; moderate in placenta, skeletal muscle and kidney; low in lung, prostate, testis, small intestine and colon., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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