ITN0680
ITN0680
- Catalog: ITN0680
- Gene/Protein: LRSAM1 TAL UNQ6496/PRO21356
- Product Description: Immunotag™ LRSM1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LRSM1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | LRSM1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | LRSAM1 TAL UNQ6496/PRO21356 |
| Accession No. | Q6UWE0 Q80ZI6 |
| Description | leucine rich repeat and sterile alpha motif containing 1(LRSAM1) Homo sapiens This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jan 2012], |
| Protein Expression | Brain,Skin,Teratocarcinoma, |
| Subcellular Localization | cytoplasm,membrane, |
| Protein Function | domain:The coiled coil domains interact with the SB domain of TSG101.,domain:The PTAP motifs mediate the binding to UEV domains.,function:E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subcellular location:Displays a punctuate distribution and localizes to a submembranal ring.,subunit:Interacts with TSG101., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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