ITN0702
ITN0702
- Catalog: ITN0702
- Gene/Protein: EDEM1 EDEM KIAA0212
- Product Description: Immunotag™ EDEM1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | EDEM1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | EDEM1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | EDEM1 EDEM KIAA0212 |
| Accession No. | Q92611 Q925U4 |
| Description | function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,similarity:Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3., |
| Protein Expression | Bone marrow,Primary B-Cells,Skin, |
| Subcellular Localization | endoplasmic reticulum,membrane,integral component of endoplasmic reticulum membrane,endoplasmic reticulum quality control compartment, |
| Protein Function | function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,similarity:Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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