ITN0707
ITN0707
- Catalog: ITN0707
- Gene/Protein: HSD17B2 EDH17B2
- Product Description: Immunotag™ DHB2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | DHB2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | DHB2 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | HSD17B2 EDH17B2 |
Accession No. | P37059 P51658 Q62730 |
Description | catalytic activity:Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H.,catalytic activity:Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH.,function:Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family., |
Cell Pathway/ Category | Steroid hormone biosynthesis,Androgen and estrogen metabolism, |
Protein Expression | Bone marrow,Epithelium,Human small intestine,Prostate, |
Subcellular Localization | endoplasmic reticulum membrane,integral component of membrane, |
Protein Function | catalytic activity:Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H.,catalytic activity:Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH.,function:Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |