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ITN0757

ITN0757
  • Catalog: ITN0757
  • Gene/Protein: GNA11 GA11
  • Product Description: Immunotag™ GNA11 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ GNA11 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein GNA11
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity GNA11 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name GNA11 GA11
Accession No. P29992 P21278 Q9JID2
Description G protein subunit alpha 11(GNA11) Homo sapiens The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013],
Cell Pathway/ Category Calcium,Vascular smooth muscle contraction,Gap junction,Long-term depression,GnRH,
Protein Expression Brain,Cervix carcinoma,Hematopoietic,Pancreas,PCR rescued clones,Retina,Tes
Subcellular Localization photoreceptor outer segment,cytoplasm,lysosomal membrane,plasma membrane,extracellular exosome,
Protein Function function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.,similarity:Belongs to the G-alpha family. G(q) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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