ITN0757
ITN0757
- Catalog: ITN0757
- Gene/Protein: GNA11 GA11
- Product Description: Immunotag™ GNA11 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | GNA11 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | GNA11 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | GNA11 GA11 |
Accession No. | P29992 P21278 Q9JID2 |
Description | G protein subunit alpha 11(GNA11) Homo sapiens The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013], |
Cell Pathway/ Category | Calcium,Vascular smooth muscle contraction,Gap junction,Long-term depression,GnRH, |
Protein Expression | Brain,Cervix carcinoma,Hematopoietic,Pancreas,PCR rescued clones,Retina,Tes |
Subcellular Localization | photoreceptor outer segment,cytoplasm,lysosomal membrane,plasma membrane,extracellular exosome, |
Protein Function | function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.,similarity:Belongs to the G-alpha family. G(q) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |