ITN0759
ITN0759
- Catalog: ITN0759
- Gene/Protein: GUCA2B
- Product Description: Immunotag™ GUC2B Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | GUC2B |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | GUC2B Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | GUCA2B |
Accession No. | Q16661 O09051 P70668 |
Description | guanylate cyclase activator 2B(GUCA2B) Homo sapiens This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. [provided by RefSeq, Nov 2015], |
Protein Expression | Blood,Colon,Placenta, |
Subcellular Localization | photoreceptor outer segment,extracellular exosome, |
Protein Function | function:Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.,similarity:Belongs to the guanylin family.,tissue specificity:Stomach and intestine., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |