ITN0822
ITN0822
- Catalog: ITN0822
- Gene/Protein: LRBA BGL CDC4L LBA
- Product Description: Immunotag™ LRBA Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LRBA |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p |
| Recommended Dilution | IHC-p 1:50-300 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1970-2050 |
| Specificity | LRBA Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | LRBA BGL CDC4L LBA |
| Accession No. | P50851 Q9ESE1 |
| Description | LPS responsive beige-like anchor protein(LRBA) Homo sapiens The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012], |
| Protein Expression | Brain,Epithelium,Kidney,Lung,Retina, |
| Subcellular Localization | lysosome,endoplasmic reticulum,Golgi apparatus,plasma membrane,membrane,integral component of membrane, |
| Protein Function | caution:Was originally (PubMed:1505956) said to be similar to yeast CDC4, but that similarity is very limited.,induction:By lipopolysaccharide (LPS).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BEACH domain.,similarity:Contains 6 WD repeats., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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