ITN0831
ITN0831
- Catalog: ITN0831
- Gene/Protein: LRP1B LRPDIT
- Product Description: Immunotag™ LRP1B Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LRP1B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p |
| Recommended Dilution | IHC-p 1:50-300 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 200-280 |
| Specificity | LRP1B Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | LRP1B LRPDIT |
| Accession No. | Q9NZR2 Q9JI18 |
| Description | LDL receptor related protein 1B(LRP1B) Homo sapiens This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by RefSeq, Jun 2016], |
| Protein Expression | Brain,Lung cancer, |
| Subcellular Localization | integral component of membrane,receptor complex, |
| Protein Function | function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis.,miscellaneous:The gene is preferentially inactivated in one histological type of lung cancer (non-small cell lung cancer (NSCLC)). May thus play an important role in tumorigenesis of NSCLCs.,similarity:Belongs to the LDLR family.,similarity:Contains 14 EGF-like domains.,similarity:Contains 32 LDL-receptor class A domains.,similarity:Contains 36 LDL-receptor class B repeats.,subunit:Binds LRPAP1, PLAU, PLAT and SERPINE1; binding is followed by internalization and degradation of the ligands.,tissue specificity:Expressed in thyroid gland and in salivary gland, as well as in adult and fetal brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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