ITN0901
ITN0901
- Catalog: ITN0901
- Gene/Protein: MYBPC2 MYBPCF
- Product Description: Immunotag™ MYPC2 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | MYPC2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 560-640 |
Specificity | MYPC2 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | MYBPC2 MYBPCF |
Accession No. | Q14324 Q5XKE0 |
Description | myosin binding protein C, fast type(MYBPC2) Homo sapiens This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively. [provided by RefSeq, Jul 2012], |
Protein Expression | Epithelium,Fetal skeletal muscle,Pooled, |
Subcellular Localization | cytosol,myosin filament, |
Protein Function | function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.,similarity:Belongs to the immunoglobulin superfamily. MyBP family.,similarity:Contains 3 fibronectin type-III domains.,similarity:Contains 7 Ig-like C2-type (immunoglobulin-like) domains., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |