ITN0903
ITN0903
- Catalog: ITN0903
- Gene/Protein: MYO1A MYHL
- Product Description: Immunotag™ MYO1A Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | MYO1A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 370-450 |
| Specificity | MYO1A Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | MYO1A MYHL |
| Accession No. | Q9UBC5 O88329 Q62774 |
| Description | myosin IA(MYO1A) Homo sapiens This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011], |
| Protein Expression | Intestine,Jejunum,Placenta, |
| Subcellular Localization | cytoplasm,microvillus,brush border,basal plasma membrane,basolateral plasma membrane,apical plasma membrane,lateral plasma membrane,myosin complex,cortical actin cytoskeleton,filamentous actin,plasma membrane raft, |
| Protein Function | disease:Defects in MYO1A are the cause of non-syndromic sensorineural deafness autosomal dominant type 48 (DFNA48) [MIM:607841]. DFNA48 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.,function:Involved in directing the movement of organelles along actin filaments .,similarity:Contains 1 myosin head-like domain.,similarity:Contains 3 IQ domains., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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