ITN0907
ITN0907
- Catalog: ITN0907
- Gene/Protein: MYO5B KIAA1119
- Product Description: Immunotag™ MYO5B Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | MYO5B |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 1120-1200 |
Specificity | MYO5B Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | MYO5B KIAA1119 |
Accession No. | Q9ULV0 P21271 P70569 |
Description | myosin VB(MYO5B) Homo sapiens The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009], |
Protein Expression | Brain,Colon, |
Subcellular Localization | myosin complex,cytoplasmic vesicle membrane,protein complex,apical cortex,recycling endosome,extracellular exosome, |
Protein Function | disease:Defects in MYO5B are a cause of microvillus inclusion disease (MVID) [MIM:251850]. MVID is characterized by onset of intractable life-threatening watery diarrhea during infancy. Two forms are recognized: early-onset MVID with diarrhea beginning in the neonatal period, and late-onset, with first symptoms appearing after 3 or 4 months of life.,similarity:Contains 1 dilute domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 6 IQ domains.,subunit:Interacts with RAB11FIP2., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |