ITN0926
ITN0926
- Catalog: ITN0926
- Gene/Protein: NDUFB3
- Product Description: Immunotag™ NDUB3 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NDUB3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 40-120 |
Specificity | NDUB3 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | NDUFB3 |
Accession No. | O43676 Q9CQZ6 |
Description | NADH:ubiquinone oxidoreductase subunit B3(NDUFB3) Homo sapiens This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012], |
Cell Pathway/ Category | Oxidative phosphorylation,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
Protein Expression | Heart,Lung, |
Subcellular Localization | mitochondrial inner membrane,mitochondrial respiratory chain complex I,integral component of membrane,extracellular exosome, |
Protein Function | function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFB3 subunit family.,subunit:Complex I is composed of 45 different subunits., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |