ITN0965
ITN0965
- Catalog: ITN0965
- Gene/Protein: NLGN1 KIAA1070
- Product Description: Immunotag™ NLGN1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NLGN1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 410-490 |
| Specificity | NLGN1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | NLGN1 KIAA1070 |
| Accession No. | Q8N2Q7 Q99K10 Q62765 |
| Description | neuroligin 1(NLGN1) Homo sapiens This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Cell adhesion molecules (CAMs), |
| Protein Expression | Brain,Duodenum,Embryo, |
| Subcellular Localization | extracellular space,Golgi apparatus,plasma membrane,integral component of plasma membrane,external side of plasma membrane,cell surface,postsynaptic density,NMDA selective glutamate receptor complex,cell junction,dendrite,filopodium tip, |
| Protein Function | function:Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses.,similarity:Belongs to the type-B carboxylesterase/lipase family.,subcellular location:Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities.,subunit:Interacts with neurexin 1-beta, neurexin 2-beta and neurexin 3-beta. Interacts through its C-terminus with DLG4/PSD-95 third PDZ domain. Interacts with AIP1 and PDZRN3., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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