ITN0983
ITN0983
- Catalog: ITN0983
- Gene/Protein: NOSIP CGI-25
- Product Description: Immunotag™ NOSIP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NOSIP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 220-300 |
| Specificity | NOSIP Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | NOSIP CGI-25 |
| Accession No. | Q9Y314 Q9D6T0 |
| Description | nitric oxide synthase interacting protein(NOSIP) Homo sapiens The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012], |
| Protein Expression | B-cell,Brain,Placenta, |
| Subcellular Localization | Golgi membrane,nucleus,cytoplasm,cytosol, |
| Protein Function | domain:The U-box-like region is a truncated U-box domain. It is unknown whether it is functional or not.,function:Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the NOSIP family.,subcellular location:Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.,subunit:Interacts with NOS1 and NOS3.,tissue specificity:Expressed in heart, brain and lung. Present in endothelial cells (at protein level)., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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