ITN0989
ITN0989
- Catalog: ITN0989
- Gene/Protein: NUP107
- Product Description: Immunotag™ NU107 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NU107 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 600-680 |
| Specificity | NU107 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | NUP107 |
| Accession No. | P57740 Q8BH74 P52590 |
| Description | nucleoporin 107(NUP107) Homo sapiens This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008], |
| Protein Expression | Epithelium,Pancreatic cancer,Uterus, |
| Subcellular Localization | kinetochore,condensed chromosome kinetochore,nuclear envelope,nuclear pore,nucleoplasm,centrosome,cytosol,membrane,nuclear pore outer ring,nuclear membrane,nuclear periphery, |
| Protein Function | function:Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the nucleoporin Nup84/Nup107 family.,subcellular location:Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores.,subunit:Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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