ITN0991
ITN0991
- Catalog: ITN0991
- Gene/Protein: NUP153
- Product Description: Immunotag™ NU153 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NU153 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 160-240 |
Specificity | NU153 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | NUP153 |
Accession No. | P49790 P49791 |
Description | nucleoporin 153(NUP153) Homo sapiens Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013], |
Protein Expression | Epithelium,Ovarian carcinoma,Testis, |
Subcellular Localization | nuclear pore,nucleoplasm,nucleolus,cytoplasm,nuclear membrane,nuclear periphery,nuclear inclusion body,nuclear pore central transport channel,nuclear pore nuclear basket, |
Protein Function | domain:Contains F-X-F-G repeats.,function:Possible DNA-binding subunit of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane.,similarity:Contains 4 RanBP2-type zinc fingers.,subcellular location:Located to the terminal ring structure of the nucleoplasmic cage.,subunit:Interacts with SENP2 and XPO5., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |