ITN1016
ITN1016
- Catalog: ITN1016
- Gene/Protein: ODC1
- Product Description: Immunotag™ DCOR Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DCOR |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 250-330 |
| Specificity | DCOR Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ODC1 |
| Accession No. | P11926 P00860 P09057 |
| Description | ornithine decarboxylase 1(ODC1) Homo sapiens This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013], |
| Cell Pathway/ Category | Arginine and proline metabolism,Glutathione metabolism, |
| Protein Expression | Esophagus,Lymph,Testis, |
| Subcellular Localization | cytoplasm,cytosol,perinuclear region of cytoplasm, |
| Protein Function | catalytic activity:L-ornithine = putrescine + CO(2).,cofactor:Pyridoxal phosphate.,enzyme regulation:Inhibited by S-nitrosylation.,online information:Ornithine decarboxylase entry,pathway:Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.,PTM:S-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues.,similarity:Belongs to the Orn/Lys/Arg decarboxylase class-II family.,subunit:Homodimer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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