ITN1076
ITN1076
- Catalog: ITN1076
- Gene/Protein: KCNK5 TASK2
- Product Description: Immunotag™ KCNK5 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | KCNK5 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 230-310 |
Specificity | KCNK5 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | KCNK5 TASK2 |
Accession No. | O95279 |
Description | potassium two pore domain channel subfamily K member 5(KCNK5) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Kidney,Placenta, |
Subcellular Localization | integral component of plasma membrane,integral component of membrane, |
Protein Function | function:pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.,miscellaneous:Inhibited by quinine, quinidine and external acidification.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |