ITN1080
ITN1080
ITN1080
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- Catalog: ITN1080
- Gene/Protein: KCNE1L AMMECR2
- Product Description: Immunotag™ KCE1L Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein KCE1L Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse Host Species Rabbit Immunogen Synthesized peptide derived from human protein . at AA range: 40-120 Specificity KCE1L Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name KCNE1L AMMECR2 Accession No. Q9UJ90 Q9QZ26 Description potassium voltage-gated channel subfamily E regulatory subunit 5(KCNE5) Homo sapiens Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome. [provided by RefSeq, Jul 2008], Protein Expression Brain,Heart,Neuron,Placenta,Subthalamic nuc Subcellular Localization plasma membrane,voltage-gated potassium channel complex,integral component of membrane, Protein Function disease:Defects in KCNE1L may be a cause of AMME complex [MIM:300194]; also known as Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis, and of additional mild abnormalities of the heart. The AMME complex is a contiguous gene deletion syndrome.,similarity:Belongs to the potassium channel KCNE family.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | KCE1L |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 40-120 |
| Specificity | KCE1L Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | KCNE1L AMMECR2 |
| Accession No. | Q9UJ90 Q9QZ26 |
| Description | potassium voltage-gated channel subfamily E regulatory subunit 5(KCNE5) Homo sapiens Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Heart,Neuron,Placenta,Subthalamic nuc |
| Subcellular Localization | plasma membrane,voltage-gated potassium channel complex,integral component of membrane, |
| Protein Function | disease:Defects in KCNE1L may be a cause of AMME complex [MIM:300194]; also known as Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis, and of additional mild abnormalities of the heart. The AMME complex is a contiguous gene deletion syndrome.,similarity:Belongs to the potassium channel KCNE family.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |