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ITN1084

ITN1084
  • Catalog: ITN1084
  • Gene/Protein: KCNG4 KCNG3
  • Product Description: Immunotag™ KCNG4 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ KCNG4 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein KCNG4
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein . at AA range: 420-500
Specificity KCNG4 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name KCNG4 KCNG3
Accession No. Q8TDN1 Q80XM3
Description potassium voltage-gated channel modifier subfamily G member 4(KCNG4) Homo sapiens Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008],
Protein Expression Brain,Muscle,PCR rescued clones,
Subcellular Localization plasma membrane,voltage-gated potassium channel complex,
Protein Function domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,function:Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.,similarity:Belongs to the potassium channel family. G subfamily.,subcellular location:Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.,subunit:Heteromultimer with KCNB1, KCNC1 and KCNF1. Does not form homomultimers.,tissue specificity:Highly expressed in brain, and at lower levels in liver, small intestine and colon.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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