ITN1122
ITN1122
- Catalog: ITN1122
- Gene/Protein: SEC61B
- Product Description: Immunotag™ SC61B Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | SC61B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Specificity | SC61B Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SEC61B |
| Accession No. | P60468 Q9CQS8 |
| Description | Sec61 translocon beta subunit(SEC61B) Homo sapiens The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Vibrio cholerae infection, |
| Protein Expression | Brain,Embryonic kidney,Epithelium,Stomach mucosa, |
| Subcellular Localization | endoplasmic reticulum,Sec61 translocon complex,endoplasmic reticulum membrane,cytosol,membrane,integral component of membrane,endoplasmic reticulum Sec complex, |
| Protein Function | function:Necessary for protein translocation in the endoplasmic reticulum.,similarity:Belongs to the SEC61-beta family.,subunit:Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma. Part of a complex composed of SEC61, SEC62 and SEC63. Interacts with SEC62., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|