ITN1135
ITN1135
- Catalog: ITN1135
- Gene/Protein: RILP PP10141
- Product Description: Immunotag™ RILP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RILP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 70-150 |
| Specificity | RILP Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RILP PP10141 |
| Accession No. | Q96NA2 Q5ND29 |
| Description | Rab interacting lysosomal protein(RILP) Homo sapiens This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology. [provided by RefSeq, Sep 2011], |
| Protein Expression | Brain,Cervix carcinoma,Kidney,Lung,Skeletal muscle,Testis,Thalamus,Uterus, |
| Subcellular Localization | mitochondrion,lysosome,lysosomal membrane,late endosome,cytosol,phagocytic vesicle membrane,late endosome membrane,ciliary basal body,protein complex, |
| Protein Function | function:Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.,similarity:Contains 1 RILP-like domain.,subcellular location:Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7 is necessary for its recruitment to phagosomes.,subunit:Homodimer. Each subunit can interact with either RAB7 or RAB34.,tissue specificity:Ubiquitous. Strongly expressed in fetal heart, heart, stomach, spleen, adrenal gland, thyroid gland, salivary gland, fetal liver, liver and lung. Poorly expressed in brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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