ITN1141
ITN1141
- Catalog: ITN1141
- Gene/Protein: RALGDS KIAA1308 RGF
- Product Description: Immunotag™ GNDS Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GNDS |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 130-210 |
| Specificity | GNDS Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RALGDS KIAA1308 RGF |
| Accession No. | Q12967 Q03385 Q03386 |
| Description | ral guanine nucleotide dissociation stimulator(RALGDS) Homo sapiens Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.[supplied by OMIM, Nov 2010], |
| Cell Pathway/ Category | Pathways in cancer,Colorectal cancer,Pancreatic cancer, |
| Protein Expression | Brain,Epithelium,Placenta,Primary B-Cells,Spleen,Thalamus, |
| Subcellular Localization | intracellular,nucleus,cytosol,brush border, |
| Protein Function | domain:The Ras-associating domain interacts with Ras.,function:Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Ras-GEF domain.,subunit:Interacts with RIT1 and RIT2., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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