ITN1165
ITN1165
- Catalog: ITN1165
- Gene/Protein: RAB13 GIG4
- Product Description: Immunotag™ RAB13 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | RAB13 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 40-120 |
| Specificity | RAB13 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RAB13 GIG4 |
| Accession No. | P51153 Q9DD03 P35286 |
| Description | RAB13, member RAS oncogene family(RAB13) Homo sapiens This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013], |
| Cell Pathway/ Category | Tight junction, |
| Protein Expression | Brain,Ovary,Placenta,PNS,Skin, |
| Subcellular Localization | intracellular,cytoplasm,Golgi apparatus,trans-Golgi network,plasma membrane,bicellular tight junction,lateral plasma membrane,lamellipodium,endocytic vesicle,cytoplasmic vesicle membrane,cytoplasmic vesicle,insul |
| Protein Function | function:Could participate in polarized transport, in the assembly and/or the activity of tight junctions.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Cytoplasmic tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions.,tissue specificity:Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|