ITN1213
ITN1213
- Catalog: ITN1213
- Gene/Protein: ARHGAP20 KIAA1391
- Product Description: Immunotag™ RHG20 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RHG20 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 800-880 |
| Specificity | RHG20 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ARHGAP20 KIAA1391 |
| Accession No. | Q9P2F6 Q6IFT4 Q6REY9 |
| Description | Rho GTPase activating protein 20(ARHGAP20) Homo sapiens The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016], |
| Protein Expression | Brain,Testis, |
| Subcellular Localization | cytosol, |
| Protein Function | caution:The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but BRWD3 is localized to Xq21 and not to Xq13.,developmental stage:Low expression is found in fetal liver.,disease:A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes.,function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed predominantly in the brain. Lower expression is found in lymph nodes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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