ITN1275
ITN1275
- Catalog: ITN1275
- Gene/Protein: PPP1R10 CAT53 FB19 PNUTS
- Product Description: Immunotag™ PP1RA Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | PP1RA |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | PP1RA Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PPP1R10 CAT53 FB19 PNUTS |
| Accession No. | Q96QC0 Q80W00 O55000 |
| Description | protein phosphatase 1 regulatory subunit 10(PPP1R10) Homo sapiens This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012], |
| Protein Expression | Bladder,Brain,Cervix carcinoma,Epithelium,Peripheral blood |
| Subcellular Localization | nuclear chromosome, telomeric region,chromatin,nucleus,nucleoplasm,PTW/PP1 phosphatase complex, |
| Protein Function | function:Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.,PTM:Phosphorylated on Ser-398 and Thr-400 by PKA within the region necessary for interaction with PPP1CA.,similarity:Contains 1 C3H1-type zinc finger.,similarity:Contains 1 TFIIS N-terminal domain.,subcellular location:Found in discrete nucleoplasmic bodies and within nucleoli.,subunit:Interacts with PPP1CA and PPP1CC.,tissue specificity:Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|