ITN1283
ITN1283
- Catalog: ITN1283
- Gene/Protein: PPP4R1 MEG1 PP4R1
- Product Description: Immunotag™ PP4R1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | PP4R1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | PP4R1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | PPP4R1 MEG1 PP4R1 |
Accession No. | Q8TF05 Q8K2V1 Q8VI02 |
Description | protein phosphatase 4 regulatory subunit 1(PPP4R1) Homo sapiens This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012], |
Protein Expression | Brain,Neuroepithelium,Pituitary,Placenta, |
Subcellular Localization | protein phosphatase 4 complex, |
Protein Function | function:Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3.,similarity:Contains 14 HEAT repeats.,subunit:Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits. Component of the PP4 complex PPP4C-PPP4R1. Interacts with HDAC3.,tissue specificity:Widely expressed with high expression in cultured mesangial cells. Isoform 1 and isoform 2 are expressed in renal tissues., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |