ITN1295
ITN1295
- Catalog: ITN1295
- Gene/Protein: SH2D3C NSP3 UNQ272/PRO309/PRO34088
- Product Description: Immunotag™ SH2D3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SH2D3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SH2D3 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SH2D3C NSP3 UNQ272/PRO309/PRO34088 |
| Accession No. | Q8N5H7 Q9QZS8 |
| Description | SH2 domain containing 3C(SH2D3C) Homo sapiens This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011], |
| Protein Expression | Amygdala,Brain,Cervix,Pancreas,Placenta,Testis, |
| Subcellular Localization | intracellular,cytoplasm,membrane, |
| Protein Function | function:Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration.,similarity:Contains 1 Ras-GEF domain.,similarity:Contains 1 SH2 domain.,subcellular location:Associated with the membrane when EGF-stimulated. Found at ruffling membranes.,subunit:Interacts with PTK2B. Isoform 2 interacts with BCAR1/CAS and NEDD9/HEF1.,tissue specificity:Ubiquitously expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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