ITN1336
ITN1336
- Catalog: ITN1336
- Gene/Protein: SLC9A1 APNH1 NHE1
- Product Description: Immunotag™ SL9A1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SL9A1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SL9A1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SLC9A1 APNH1 NHE1 |
| Accession No. | P19634 Q61165 P26431 |
| Description | solute carrier family 9 member A1(SLC9A1) Homo sapiens This gene encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. The encoded protein is a plasma membrane transporter that is expressed in the kidney and intestine. This protein plays a central role in regulating pH homeostasis, cell migration and cell volume. This protein may also be involved in tumor growth. [provided by RefSeq, Sep 2011], |
| Cell Pathway/ Category | Cardiac muscle contraction,Regulates Actin and Cytoskeleton, |
| Protein Expression | Heart,Hippocampus,Kidney,Placenta,Platelet, |
| Subcellular Localization | nucleoplasm,cytoplasm,mitochondrion,endoplasmic reticulum,endoplasmic reticulum membrane,plasma membrane,integral component of plasma membrane,focal adhesion,cell surface,intercalated disc,integral component of membrane, |
| Protein Function | caution:The region between transmembrane regions M4 and M5 and between M6 and M7 (also termed intracellular loops IL2 and IL4, respectively) seem to be localized at least in part in the membrane. The hydrophobic region H10 is proposed to be located within the membrane.,function:Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.,miscellaneous:Inhibited by amiloride and 5-amino-substituted derivatives and activated in a cooperative fashion by intracellular H(+). In quiescent cells upon growth factor stimulation, the apparent affinity for internal H(+) is increased, resulting in a persistent rise in cytoplasmic pH.,PTM:O-glycosylated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,subunit:Interacts with tescalcin, CHP and CHP2.,tissue specificity:Kidney and intestine., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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