ITN1348
ITN1348
- Catalog: ITN1348
- Gene/Protein: SLC34A1 NPT2 SLC17A2
- Product Description: Immunotag™ NPT2A Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NPT2A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 260-340 |
| Specificity | NPT2A Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SLC34A1 NPT2 SLC17A2 |
| Accession No. | Q06495 Q60825 Q06496 |
| Description | solute carrier family 34 member 1(SLC34A1) Homo sapiens This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009], |
| Protein Expression | Colon,Kidney, |
| Subcellular Localization | cytoplasm,endosome,plasma membrane,integral component of plasma membrane,brush border,cell surface,integral component of membrane,apical plasma membrane,intrinsic component of plasma membrane,brush border membrane,vesicle,G |
| Protein Function | disease:Defects in SLC34A1 are the cause of hypophosphatemic nephrolithiasis/osteoporosis type 1 (NPHLOP1) [MIM:612286]. Hypophosphatemia results from idiopathic renal phosphate loss. It contributes to the pathogenesis of hypophosphatemic urolithiasis (formation of urinary calculi) as well to that of hypophosphatemic osteoporosis (bone demineralization).,function:May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx.,similarity:Belongs to the SLC34A transporter family.,subunit:Interacts via its C-terminal region with PDZK2.,tissue specificity:Kidney and lung., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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