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ITN1348

ITN1348
  • Gene/Protein: SLC34A1 NPT2 SLC17A2
  • Product Description: Immunotag™ NPT2A Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ NPT2A Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein NPT2A
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 260-340
Specificity NPT2A Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name SLC34A1 NPT2 SLC17A2
Accession No. Q06495 Q60825 Q06496
Description solute carrier family 34 member 1(SLC34A1) Homo sapiens This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],
Protein Expression Colon,Kidney,
Subcellular Localization cytoplasm,endosome,plasma membrane,integral component of plasma membrane,brush border,cell surface,integral component of membrane,apical plasma membrane,intrinsic component of plasma membrane,brush border membrane,vesicle,G
Protein Function disease:Defects in SLC34A1 are the cause of hypophosphatemic nephrolithiasis/osteoporosis type 1 (NPHLOP1) [MIM:612286]. Hypophosphatemia results from idiopathic renal phosphate loss. It contributes to the pathogenesis of hypophosphatemic urolithiasis (formation of urinary calculi) as well to that of hypophosphatemic osteoporosis (bone demineralization).,function:May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx.,similarity:Belongs to the SLC34A transporter family.,subunit:Interacts via its C-terminal region with PDZK2.,tissue specificity:Kidney and lung.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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