ITN1352
ITN1352
- Catalog: ITN1352
- Gene/Protein: SLC12A2 NKCC1
- Product Description: Immunotag™ S12A2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | S12A2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | S12A2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SLC12A2 NKCC1 |
| Accession No. | P55011 P55012 |
| Description | solute carrier family 12 member 2(SLC12A2) Homo sapiens The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2012], |
| Cell Pathway/ Category | Vibrio cholerae infection, |
| Protein Expression | Brain,Colon,Eye, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,membrane,integral component of membrane,apical plasma membrane,extracellular exosome,extracellular vesicle, |
| Protein Function | function:Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SLC12A transporter family.,tissue specificity:Expressed in many tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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